Magnetic susceptibility contrast variations in multiple sclerosis lesions
نویسندگان
چکیده
منابع مشابه
Magnetic Susceptibility Contrast Variations in Multiple Sclerosis (ms) Lesions Observed at 7t
MAGNETIC SUSCEPTIBILITY CONTRAST VARIATIONS IN MULTIPLE SCLEROSIS (MS) LESIONS OBSERVED AT 7T Xu Li, Hongjun Liu, Daniel M Harrison, Craig K Jones, Jiwon Oh, Peter A Calabresi, and Peter C.M. van Zijl F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United Stat...
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Background: Multiple Sclerosis (MS) syndrome is a type of Immune-Mediated disorder in the central nervous system (CNS) which destroys myelin sheaths, and results in plaque (lesion) formation in the brain. From the clinical point of view, investigating and monitoring information such as position, volume, number, and changes of these plaques are integral parts of the controlling process this dise...
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BACKGROUND AND PURPOSE Magnetic susceptibility measured with quantitative susceptibility mapping has been proposed as a biomarker for demyelination and inflammation in patients with MS, but investigations have mostly been on white matter lesions. A detailed characterization of cortical lesions has not been performed. The purpose of this study was to evaluate magnetic susceptibility in both cort...
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Two patients are described in whom computerised tomography revealed contrast-enhanced lesions in the early stages of multiple sclerosis. Such lesions may be differentiated from tumours by their transient nature, lack of space-occupying effect, and localisation in the white matter. Contrast enhancement in demyelinating disease is probably related to local breakdown of the blood-brain barrier.
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2015
ISSN: 1053-1807
DOI: 10.1002/jmri.24976